Results 121 to 130 of about 162,803 (294)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Personal Inquiry (PI): Designing for Evidence-based Inquiry Learning across Formal and Informal Settings

open access: yes, 2014
The aim of this project is to support children aged 11-14 in coming to understand themselves and their world through a new approach of scripted inquiry learning. With the aid of software running on both mobile and desktop computers, children will be able
Sharples, M, Open University
core  

Peningkatan Keterampilan Proses Sains Dasar Dengan Pendekatan Open-inquiry [PDF]

open access: yes, 2014
Tujuan dari penelitian tindakan ini yaitu untuk mengetahui secara komprehensif upaya peningkatan keterampilan proses sains dasar anak kelompok B di TK Muslimat 02 Singosari Malang. Penelitian menggunakan model Kemmis dan McTaggart.
AISIYAH, L. N. (LAILY)
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Inquiry-based learning pedagogies in the arts and social sciences: purposes, conceptions and approaches

open access: yes, 2009
This paper discusses themes arising from meta-analysis of an extensive body of ‘theory of change’ data associated with inquiry-based learning initiatives in arts and social sciences disciplines in one UK university.
Philippa Levy (17320321)   +1 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Open access on a zero budget: a case study of Postcolonial Text

open access: yesInformation Research: An International Electronic Journal, 2007
Introduction. The founding of a new open access journal is described in terms of its use of the open source software Open Journal Systems, its contribution to a new field of inquiry and its ability to operate on a zero budget in terms of regular ...
John Willinsky, Ranjini Mendis
doaj  

EFEKTIVITAS MODEL OPEN INQUIRY TERHADAP KETERAMPILAN PROSES SAINS PADA MATERI EKOSISTEM

open access: yesJurnal Inovasi Pendidikan dan Sains, 2020
Tujuan penelitian  ini untuk mengetahui efektivitas model open inquiry terhadap keterampilan proses sains pada materi ekosistem di MAN 1 Indramayu.
Eva Yuliana
doaj  

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