Results 1 to 10 of about 2,669 (201)

Open necrosectomy in acute pancreatitis–obsolete or still useful? [PDF]

World Journal of Emergency Surgery, 2020
Background Multiple organ failure and early surgery are associated with high morbimortality after open necrosectomy. Data are mostly derived from historical cohorts with early necrosectomy bereft of step-up treatment algorithm implementation.
Henrik Leonard Husu, Jouni Antero Kuronen, Ari Kalevi Leppäniemi, Panu Juhani Mentula   +3 more
doaj   +10 more sources

A step-up approach, or open necrosectomy for necrotizing pancreatitis [PDF]

New England Journal of Medicine, 2010
Necrotizing pancreatitis with infected necrotic tissue is associated with a high rate of complications and death. Standard treatment is open necrosectomy. The outcome may be improved by a minimally invasive step-up approach.In this multicenter study, we randomly assigned 88 patients with necrotizing pancreatitis and suspected or confirmed infected ...
De Waele, Jan
core   +20 more sources

Open necrosectomy is feasible as a last resort in selected cases with infected pancreatic necrosis: a case series and systematic literature review [PDF]

World Journal of Emergency Surgery, 2020
Background Acute pancreatitis is a common inflammatory pancreatic disorder, often caused by gallstone disease and frequently requiring hospitalization.
Lucia Ilaria Sgaramella, Angela Gurrado, Alessandro Pasculli, Francesco Paolo Prete, Fausto Catena, Mario Testini   +5 more
doaj   +6 more sources

Open necrosectomy combined with continuous positive drainage and prophylactic diverting loop ileostomy for late infected pancreatic necrosis: a retrospective cohort study [PDF]

BMC Gastroenterology, 2020
Background To evaluate an innovative open necrosectomy strategy with continuous positive drainage and prophylactic diverting loop ileostomy for the management of late infected pancreatic necrosis (LIPN).
Dong-Guang Niu, Wei-Qin Li, Qian Huang, Fan Yang, Wei-Liang Tian, Chen Li, Lian-An Ding, Hong-Chun Fang, Yun-Zhao Zhao   +8 more
doaj   +2 more sources

Focused open necrosectomy in necrotizing pancreatitis. [PDF]

HPB (Oxford), 2013
The control of sepsis is the primary goal of surgical intervention in patients with infected necrosis. Simple surgical approaches that are easy to reproduce may improve outcomes when specialists in endoscopy are not available. The aim of the present study was to describe the experience with a focused open necrosectomy (FON) in patients with infected ...
Pupelis G, Fokin V, Zeiza K, Plaudis H, Suhova A, Drozdova N, Boka V.   +6 more
europepmc   +4 more sources

Cost Analysis and Outcomes of Endoscopic, Minimal Access and Open Pancreatic Necrosectomy [PDF]

Annals of Surgery Open, 2021
Objectives:. To assess both individual patient and institutional costs as well as outcomes in patients with pancreatic necrosis who underwent either endoscopic, minimal access or open pancreatic necrosectomy.
Rebecca Saunders, MBChB, Faye E. Hughes, BSc, Jonathan C. Evans, MRCP, FRCR, Howard L. Smart, DM, FRCP, Paula Ghaneh, MD, FRCS, Jayapal Ramesh, FRCR, Robert Sutton, DPhil, FRCS, Christopher M. Halloran, BSc, MD, FRCS, SFHEA   +7 more
doaj   +3 more sources

Extended Open Transgastric Necrosectomy (EOTN) as a Safer Procedure for Necrotizing Pancreatitis [PDF]

Journal of Clinical and Diagnostic Research, 2014
The treatment of infected necrotizing pancreatitis has evolved from time to time and the success of surgical intervention depends on the timing of necrosectomy. Bacterial infection occurs in 40–70% of patients with necrotizing pancreatitis. Infection is
Prasad Sasnur, Ravindra Nidoni, Ramakanth Baloorkar, Vikram Sindgikar, Bharat Shankar   +4 more
doaj   +3 more sources

Surgery for necrotizing acute pancreatitis: surgical approach, morbidity and challenges encountered: experience from a tertiary care hepatopancreatobiliary unit in Sri Lanka [PDF]

Frontiers in Surgery
BackgroundInfected pancreatic necrosis (IPN) remains a life-threatening complication of acute pancreatitis. While minimally invasive “step-up” strategies are now standard, their implementation in resource-limited settings is often constrained by ...
Duminda Subasinghe, Ravindri Jayasinghe, Nilesh Fernandopulle, Vihara Dassanayake, Sivasuriya Sivaganesh   +4 more
doaj   +2 more sources

Endoscopic Versus Surgical Management for Infected Necrotizing Pancreatitis and Walled-Off Necrosis: A Systematic Review of Randomized Controlled Trials [PDF]

Medicina
Background and Objectives: Infected necrotizing pancreatitis and walled-off necrosis are associated with substantial morbidity and mortality. The evolution from open necrosectomy to minimally invasive and endoscopic strategies has improved outcomes, yet ...
Manuela Mastronardi, Giada Moghnie, Sara Crociato, Chiara Menghini, Alessio Biagio Filippo Giordano, Paola Germani, Margherita Sandano, Nicolò de Manzini, Alan Biloslavo   +8 more
doaj   +2 more sources

Risk Factors Influencing Mortality in Open Necrosectomy for Acute Pancreatitis: A Comparative Analysis. [PDF]

J Clin Med
Background and Objectives: Patients undergoing open necrosectomy (ON) for acute pancreatitis (AP) often face high morbidity and mortality rates. This study aims to identify risk factors associated with adverse outcomes by comparing survivors and non-survivors of ON.
Mihoc T, Pirvu C, Dobrescu A, Brebu D, Macovei AMO, Popa ZL, Pantea S.   +6 more
europepmc   +3 more sources