Results 11 to 20 of about 2,669 (201)

Evaluating the role of the Minimal Incision Retroperitoneal Necrosectomy (MIRN) in the management of infected pancreatic necrosis: Experience from a tertiary care center

Surgery Open Science, 2023
Background: The conventional open necrosectomy was associated with high mortality and morbidities like secondary organ failure, incisional hernia, enterocutaneous fistula, and external pancreatic fistula.
Mohanasundaram Avudiappan, Venu Bhargava, Aditya Kulkarni, Mandeep Kang, Surinder Singh Rana, Rajesh Gupta   +5 more
doaj   +3 more sources

The role of open necrosectomy in the current management of acute necrotizing pancreatitis: a review article. [PDF]

ISRN Surg, 2013
The optimal management of necrotizing pancreatitis continues to evolve. Currently, conservative intensive care treatment represents the primary therapy of acute severe necrotizing pancreatitis, aiming at prevention of organ failure. Following this mode of treatment most patients with sterile necroses can be managed successfully.
Vasiliadis K, Papavasiliou C, Al Nimer A, Lamprou N, Makridis C.   +4 more
europepmc   +4 more sources

Paradigm shift away from open surgical necrosectomy toward endoscopic interventions for necrotizing pancreatitis

Gastrointestinal Intervention, 2014
AbstractInterventions for infected and symptomatic walled-off pancreatic necrosis (WOPN) have undergone a paradigm shift away from open surgical necrosectomy toward endoscopic intervention such as transmural drainage and necrosectomy. Recent multicenter studies and evidence-based guidelines have suggested the safety and efficacy of endoscopic ...
Cho, Jae Hee, Kim, Yoon Jae, Kim, Yeon Suk   +2 more
openaire   +3 more sources

Retroperitoneal versus open intraperitoneal necrosectomy in step-up therapy for infected necrotizing pancreatitis: A meta-analysis

International Journal of Surgery, 2018
Step-up therapy is the recommended therapy for infected necrotizing pancreatitis (INP). However, the most appropriate secondary therapy for use after initial drainage has not been fully determined. This meta-analysis was designed to evaluate the efficacy and safety of retroperitoneal versus open intraperitoneal necrosectomy as part of a step-up ...
Yun-Bing Wang, Xiao-Li Yang, Long Chen, Zheng-Ju Chen, Chun-Mu Miao, Jin Xia   +5 more
openaire   +4 more sources

Acute Necrotizing Pancreatitis—Advances and Challenges in Management for Optimal Clinical Outcomes [PDF]

Medicina
Acute necrotizing pancreatitis (ANP), characterized by necrosis of pancreatic and/or peripancreatic tissues, is a potentially severe and life-threatening complication of acute pancreatitis, exhibiting a considerable mortality rate, particularly in the ...
Ioana Dumitrascu, Narcis Octavian Zarnescu, Eugenia Claudia Zarnescu, Mihai Radu Pahomeanu, Alexandru Constantinescu, Dana Galieta Minca, Radu Virgil Costea   +6 more
doaj   +2 more sources

Outcomes From Minimal Access Retroperitoneal and Open Pancreatic Necrosectomy in 394 Patients With Necrotizing Pancreatitis

Annals of Surgery, 2016
To examine the outcomes from minimal access retroperitoneal pancreatic necrosectomy (MARPN) and open pancreatic necrosectomy (OPN) for severe necrotizing pancreatitis in a single center.The optimal management of severe pancreatic necrosis is evolving with a few large center single series.Between 1997 and 2013, patients with necrotizing pancreatitis at ...
Gomatis, I, Halloran, CM, Ghaneh, P, Raraty, M, Polydoros, F, Evans, JC, Smart, HL, Yagati-Satchidanand, R, Garry, JM, Whelan, PA, Hughes, FE, Sutton, R, Neoptolemos, JP   +12 more
openaire   +4 more sources

Laparoscopic retroperitoneal necrosectomy in patients with necrotizing pancreatitis: addressing the limitations of traditional treatment options [PDF]

BMC Gastroenterology
Background Laparoscopic retroperitoneal necrosectomy (LRN) is a novel minimally invasive approach for treating infected necrotizing pancreatitis. Our study aims to evaluate the safety and effectiveness of LRN for pancreatic necrosis at a single center ...
Jinjian Li, Zihao Huang, Bo Shen, Hong Yu   +3 more
doaj   +2 more sources

Immediate Endoscopic Necrosectomy for Walled-Off Pancreatic Necrosis: A First-Choice Option? [PDF]

Dig Endosc
Digestive Endoscopy, Volume 38, Issue 1, January 2026.
Hamada T, Fujisawa T, Nakai Y, WONDERFUL Study Group in Japan.   +3 more
europepmc   +2 more sources

Endoscopic Step-up Approach for Walled-off Necrosis After Acute Pancreatitis. [PDF]

DEN Open
ABSTRACT This review outlines current interventional strategies for treating symptomatic walled‐off necrosis (WON) after necrotizing pancreatitis. Mortality from acute pancreatitis has improved, but late mortality, particularly from infected necrosis, remains a challenge. WON requires invasive treatment in cases of infection or symptoms.
Mukai S, Sofuni A, Tsuchiya T, Tanaka R, Tonozuka R, Matsunami Y, Nagai K, Kojima H, Minami H, Hirakawa N, Asano K, Shionoya K, Hama K, Itoi T.   +13 more
europepmc   +2 more sources

Endoscopic Transmural Necrosectomy: Timing, Indications, and Methods [PDF]

Clinical Endoscopy, 2020
Walled-off necrosis is considered one of the most severe complications after an episode of severe acute pancreatitis. Traditionally, percutaneous drainage is selected as the first treatment step, while open surgery can be planned as a secondary option if
Rungsun Rerknimitr
doaj   +1 more source