Results 131 to 140 of about 779,176 (309)
An open chat with… Johannes Herrmann
Johannes Herrmann is a Professor of Cell Biology at the University of Kaiserslautern in Germany. His research focus is centred on the biogenesis of mitochondrial proteins.
Ioannis Tsagakis, Johannes Herrmann
doaj +1 more source
Global organizations are still facing challenges in achieving sustainable performance despite the surge in digital technologies. It is imperative that firms invest in digital capabilities to secure sustainable market performance in the face of a barrage ...
Aixia Chen, Ling Li, Waseem Shahid
doaj +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Resilience to social stress: is it in the blood?
Ruzhica Bogeska
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Predator-in-Chief: Wolves in Editors’ Clothing
Rod J. Rohrich, MD +1 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Towards an Expert Network in Open Standards and Open Source Software: Research, Expertise and Synergy for Open and Libres Standards and Software (RESOLL) - Version 2.0 [PDF]
CIRANO and its partners are proposing the creation of an Expert Network in Open Standards and Open Source Software (Research, Expertise and Synergy for Open and Libres Standards and Software-RESOLL), which would be a partnership between information ...
Adel El Zaïm, Robert Gérin-Lajoie
core
Rod J. Rohrich, MD, Aaron Weinstein, MS
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

