Results 61 to 70 of about 68,272 (311)

Automated Stability Analysis of Soil Slopes [PDF]

E3S Web of Conferences, 2019
Herein there is a description of algorithm of the automated forecast of stability for soil slope structures including input of initial data regarding physical and mechanical properties and geometrical parameters of a structure, building of the most ...
Karablin Mikhail, Gurev Dmitry, Prostov Sergey   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Application of Raman-infrared spectroscopy in the evaluation of organic matter characteristics and thermal maturity of highly-to overmature source rocks

Unconventional Resources
With the increasing depletion of conventional oil and gas resources, deep to ultra-deep petroleum resources have become a critical direction for global energy strategies. The scientific evaluation of highly-to overmature source rocks developed in deep to
Zhuanghao Peng, Xiangchun Chang, Guanlong Zhang, Bingbing Shi, Ruichao Guo, Junjian Zhang, Chenyu Wang, Shangbin Wang, Yuxuan Li, Zhaolin Li   +9 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Review on seismic response of tunnel engineering: from dynamic characteristics of rock mass to structural earthquake-resistant analysis

Meitan xuebao
Although tunnel structures are confined by the surrounding strata, and relative movement between the structure and strata is not obvious under seismic loads, resulting in significantly superior seismic performance compared to surface structures, they are
Yujing JIANG, Xingda WANG, Xuepeng ZHANG
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Research on Dominant Factors and Control Technologies for Instability in Cross-Mining Roadway

Eng
To investigate the dominant factors and instability mechanism of surrounding rock deformation in cross-mining roadways, a systematic study was conducted using theoretical analysis, numerical simulation, and response surface methodology to examine the ...
Hao Wang, Miao Chen, Jiangwei Liu, Peidong Li, Wenfei Wang, Xianghan Xu, Hui Zhou   +6 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Experimental study on pulse gas presplitting grouting in water-rich muddy silt layer in open-pit coal mine

Meikuang Anquan
To address the challenges of non-uniform grout diffusion and the difficulty in forming a continuous water cutoff curtain in water-rich muddy silt layers of open-pit coal mines, a novel method combining high-pressure pulsed gas pre-splitting for soil ...
Yan FENG, Yanbo ZHANG, Qinglong YANG, Yanbing XU, Lei ZHANG, Ning HOU   +5 more
doaj   +1 more source

Defence system from water of the open pit Gračanica - Gacko [PDF]

, 2015
The open pit Gračanica - Gacko has very complex conditions of watering with occurrences of significant inflow of water as the result of short-term precipitation of high-intensity.
Kržanović Daniel, Rajković Radmilo, Mikić Miomir, Stepanović Saša   +3 more
core   +1 more source