Results 91 to 100 of about 2,140,683 (299)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Local Lighting Control in Open-Plan Offices: The Influence of Office Lay-Out [PDF]
, 2018 Highly granular lighting control involves switching on and off luminaires based on individual occupancy. The resulting high frequency of lighting changes can distract the office workers and negatively impact their work performance. In a cubicle office, this might be less of an issue than in an office without partitions, as users do not have an overview
de Bakker, C. +4 more
openaire +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
MANAJEMEN RUANG TERBUKA HIJAU di KOTA SEMARANG [PDF]
, 2017 The problems encountered in Open Green Space Management in the city of Semarang is the absence of good planning, organizing and mobilization in the field of human resources. This study aims to determine the management of open green space of Semarang City
Ferdinand, Harianja
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Buildings, 2018 Open-plan offices have lower construction costs, allowing for significant savings in space and, according to designers, facilitate communication between workers, thus, improving collaboration, as well as the exchange of ideas.
Gino Iannace +2 more
doaj +1 more source
Office design and health: a systematic review [PDF]
, 2017 Aim: To carry out a systematic review of recent research into the effects of workplace design, comparing individual with shared workspaces, on the health of employees. Methods: The research question was "Does workplace design (specifically individual
Harding, T +7 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Megaron, 2015 At the present day spaces should provide appropriate conditions in terms of physical environment elements in addition to being functional and aesthetic. To provide comfort conditions is important in terms of performing activities in the space without any
Kasım Çelik +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source