Results 121 to 130 of about 21,254,823 (295)
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
THE INVESTIGATION OF OPEN-PLAN OFFICE SOUND’S EFFECT ON STAFF’S COGNITIVE PERFORMANCE [PDF]
Salāmat-i kār-i ĪrānINTRODUCTION: Exposure to environmental sounds (noise pollution) is a key global public health concern that has implications for health and well-being (1).
Mohammad Ghashghaei +3 more
doaj
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Open-plan layout: a workplace evaluation of small offices in Hong Kong
Hong Kong is a very densely populated city but offers an excellent environment for many business owners to run their business in South-East Asia region. However, the lack of space and great demand for office makes rental very expensive in Hong Kong.
Anita In Yee Lam (21271775)
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, 1991 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.1991-Mode of access: Internet from the Oregon Government ...
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LUMINOUS ENVIRONMENT AND OCCUPANT’S SATISFACTION AT OPEN-PLAN OFFICE (Case Study: Jawa Pos Office, Grha Pena 4th Floor, Surabaya) [PDF]
, 2009 Open-plan office provides a spacious workspace for a wide range of work-related activities and a lot of chances to rearrange the workstation. In the workspace, a good lighting condition should be provided.
Dinapradipta, Asri, Nurdiah, Esti Asih
core +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Open-plan Office Concepts Determine Effective Facilities Space Management
Open-plan Office Concepts Determine Effective Facilities Space Management. Open-plan layout is the most predominant work-setting and office designs are changing substantially towards this style.
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