Results 61 to 70 of about 165,562 (297)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Open-plan office noise increases stress and worsens mood: we’ve measured the effects

open access: yes, 2021
[Extract] If you’ve ever felt your noisy open-plan office makes you cranky and sends your heart racing, our new research shows you aren’t imagining it.Prior to the pandemic 70% of office-based employees worked in open-plan offices.
Sander, Elizabeth J
core  

Does open-plan office environment support creativity? The mediating role of activated positive mood

open access: yesCreativity Studies, 2020
This study examines how perceived physical office environment features affect occupants’ creativity through positive moods. Based on a sample of 181 occupants in open-plan offices, we found that perceived spatial organization features had a positive ...
Szu-Yin Lin, Hsin-I Chang
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Study of the Acoustic Suitability of an Open Plan Office Based on STI and DL2 Simulations

open access: yesArchives of Acoustics, 2013
Many business offices around the world are organized as open plan offices. Therefore, studies about the acoustic comfort of the people who work in them have become increasingly important.
Carolina Reich Marcon PASSERO   +1 more
doaj  

Sickness absence associated with shared and open-plan offices – a national cross sectional questionnaire survey

open access: yesScandinavian Journal of Work, Environment & Health, 2011
OBJECTIVE: The aim of this study was to examine whether shared and open-plan offices are associated with more days of sickness absence than cellular offices.
Jan H Pejtersen   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Newcomer Socialisation Tactics and Proactive Behaviours Within an Open Plan Office Environment

open access: yes, 2021
Newcomer socialisation is regarded as an important facet of organisational development. Nonetheless, extensive research publications on newcomer socialisation have been relatively unrelated to the physical workspace context.
Protheroe, Jamie
core  

Differences in Occupants’ Satisfaction and Perceived Productivity in High- and Low-Performance Offices

open access: yesBuildings, 2019
This paper reports the results from a dataset comprising 9794 post-occupancy evaluation (POE) surveys from 77 Australian open-plan offices. This paper specifically focuses on a sub-set of 20 offices (n = 2133), identified from ranking 10 offices each ...
Özgür Göçer   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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