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The interview of Gela Dumbadze, Ambassador Extraordinary and Plenipotentiary of Georgia to Ukraine, offers un account of the cooperation mechanisms between Ukraine and Georgia, various spheres for cooperation, and bilateral relations, which often recede from view but have great potential. The example of such interaction is exchange between the Ministry
openaire +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Fostering Openness in Education: Considerations for Sustainable Policy-Making
This paper reviews a framework to support the co-creation of policies to sustainably foster Open Education. The framework has been derived from a comprehensive review of public and Open Education policy documents and related literature, as well as ...
Javiera Atenas +4 more
doaj +3 more sources
Research outlets are increasingly adopting open data policies as a requisite for publication, including studies with human subjects data. We investigated whether open data policies influence participants' rate of consent by randomly assigning ...
Jorden A Cummings +2 more
doaj +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
In the context of a growing international focus on open access publishing options and mandates, this paper explores the extent to which the ideals of ‘openness’ are also being applied to physical knowledge resources and research spaces. This study, which
Katie Wilson +6 more
doaj +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Providing a model for Open Science Facilitator Policies in Iran
Open science is the platform for the science or scientific outputs that need to be managed transparently from the beginning to the end and be accessible to the society.
Shima Moradi
doaj

