Results 51 to 60 of about 3,014,186 (301)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

A Very Long Embargo: Journal Choice Reveals Active Non-Compliance with Funder Open Access Policies by Australian and Canadian Neuroscientists

open access: yesLiber Quarterly: The Journal of European Research Libraries, 2018
Research funders around the world have implemented open access policies that require funded research to be made open access, usually by self-archiving, within 12 months of publication.
Shaun Yon-Seng Khoo, Belinda Po Pyn Lay
doaj   +1 more source

Regional Trade Integration in Southern Africa: Critical Policy Issues [PDF]

open access: yes, 2000
The aim of this paper is to highlight key issues arising from regional trade integration in the Southern African Development Community (SADC) as well as the concomitant policies required to facilitate the trade process.
Kalenga, Paul
core  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Attitudes towards Open Access Books in the European Research Area

open access: yesLiber Quarterly: The Journal of European Research Libraries
This paper examines the challenges and opportunities of publishing Open Access (OA) books within the European Research Area (ERA), drawing on data collected through the PALOMERA project.
Gabriela Manista   +2 more
doaj   +1 more source

FOSTER D2.1 - Technical protocol for rich metadata categorization and content classification [PDF]

open access: yes, 2014
FOSTER aims to set in place sustainable mechanisms for EU researchers to FOSTER OPEN SCIENCE in their daily workflow, supporting researchers optimizing their research visibility and impact and the adoption of EU open access policies in line with the EU ...
Davidson, Joy   +4 more
core  

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

Open Door Policies: Measuring Impact Using Attitude Surveys [PDF]

open access: yes, 1995
This study examines employee perceptions of an Open Door Complaint System from both those who have filed claims and those who have not. Our sample includes over 4000 employees working in a Fortune 100 company.
Blancero, Donna   +1 more
core   +1 more source

Practical Open-Loop Optimistic Planning [PDF]

open access: yes, 2019
We consider the problem of online planning in a Markov Decision Process when given only access to a generative model, restricted to open-loop policies - i.e. sequences of actions - and under budget constraint.
D Silver   +7 more
core   +3 more sources

Home - About - Disclaimer - Privacy