Results 261 to 270 of about 1,440,104 (391)

Cyclic Peptide–Polymer Conjugate Nanotubes for Delivery of SN‐38 in Treatment of Colorectal Cancer Model

Advanced Healthcare Materials, EarlyView.
This study develops cyclic peptidepolymer conjugate nanotubes with hydrophobic, drug‐rich cores to enhance drug loading and stability, and demonstrates their responsive disassembly, pharmacokinetics, and anti‐tumour efficacy in colorectal cancer models using the anticancer drug SN‐38.
Sophie K. Hill, Min Zeng, Santhosh Kalash Rajendrakumar, Robert Dallmann, Sébastien Perrier   +4 more
wiley   +1 more source

Nested open reading frame (ORF) 7 reverse transcription polymerase chain reaction and ORF5 phylogenetic refinement for enhanced detection and genetic classification of porcine reproductive and respiratory syndrome virus-2 in Thailand. [PDF]

Vet World
Jantafong T, Karnbunchob N, Tanomsridachchai W, Mutthi P, Pavasutthipaisit S.   +4 more
europepmc   +1 more source

Open Reading Frame 4 Is Not Essential in the Replication and Infection of Genotype 1 Hepatitis E Virus. [PDF]

Viruses, 2023
Bai H, Ami Y, Suzaki Y, Doan YH, Muramatsu M, Li TC.   +5 more
europepmc   +1 more source

An inhibitory effect of the sequence-conserved upstream open-reading frame on the translation of the main open-reading frame of HsfB1 transcripts in Arabidopsis.

Plant, Cell and Environment, 2012
Xujun Zhu, S. Thalor, Yoshihiro Takahashi, T. Berberich, T. Kusano   +4 more
semanticscholar   +1 more source

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

TIdeS: A Comprehensive Framework for Accurate Open Reading Frame Identification and Classification in Eukaryotic Transcriptomes. [PDF]

Genome Biol Evol
Maurer-Alcalá XX, Kim E.
europepmc   +1 more source

BONCAT-based Profiling of Nascent Small and Alternative Open Reading Frame-encoded Proteins. [PDF]

Bio Protoc, 2023
Cao X, Chen Y, Khitun A, Slavoff SA.
europepmc   +1 more source

Translational regulation of Arabidopsis XIPOTL1 is modulated by phosphocholine levels via the phylogenetically conserved upstream open reading frame 30.

Journal of Experimental Botany, 2012
F. Alatorre-Cobos, Alfredo Cruz-Ramírez, Celine A. Hayden, Claudia-Anahí Pérez-Torres, Anne-Laure Chauvin, E. Ibarra-Laclette, Erika Alva-Cortés, R. Jorgensen, L. Herrera-Estrella   +8 more
semanticscholar   +1 more source

A Robust Heparin‐Mimicking Polyglycerol‐Based Coating for Blood‐Contacting Devices with Long‐Term Hemocompatibility and Preliminary Anti‐Inflammatory Properties

Advanced Healthcare Materials, EarlyView.
A robust heparin‐mimicking coating based on sulfated polyglycerol is constructed via layer‐by‐layer assembly on bloodcontacting surfaces. The coating exhibits long‐term anticoagulant and anti‐inflammatory properties by resisting protein adsorption, preventing platelet activation, and suppressing immune responses, offering a promising strategy for ...
Kunpeng Liu, Philip Nickl, Jun Feng, Rainer Haag   +3 more
wiley   +1 more source

An Insulin Upstream Open Reading Frame (INSU) Is Present in Skeletal Muscle Satellite Cells: Changes with Age. [PDF]

Cells
Liu QR, Zhu M, Salekin F, McCoy BM, Kennedy V, Tian J, Mazucanti CH, Chia CW, Egan JM.   +8 more
europepmc   +1 more source