Open reading frame - Open Access .click

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Bioprospecting Open Reading Frames for Peptide Effectors

2013
Recent successes in the development of small-molecule antagonists of protein-protein interactions designed based on co-crystal structures of peptides bound to their biological targets confirm that short peptides derived from interacting proteins can be high-value ligands for pharmacologic validation of targets and for identification of druggable sites.
Ling, Xiong, Charles, Scott
openaire +2 more sources

Coupling of Open Reading Frames by Translational Bypassing

Annual Review of Biochemistry, 2000
▪ Abstract Translational bypassing joins the information found within two disparate open reading frames into a single polypeptide chain. The underlying mechanism centers on the decoding properties of peptidyl-transfer RNA (tRNA) and involves three stages: take-off, scanning, and landing.
A J, Herr, J F, Atkins, R F, Gesteland
openaire +2 more sources

Engineering crop performance with upstream open reading frames

Trends in Plant Science
Plants intricately regulate the expression of protein-coding genes at multiple stages - including mRNA transcription, translation, decay, and protein degradation - to control growth, development, and responses to environmental challenges. Recent research highlights the importance of translational reprogramming as a pivotal mechanism in regulating gene ...
Rui Mou, Ruixia Niu, Ruoying Yang, Guoyong Xu +3 more
openaire +2 more sources

Open Reading Frame

2011
+4 more sources

Cervical cancer prevention and control in women living with human immunodeficiency virus

Ca-A Cancer Journal for Clinicians, 2021
Philip E Castle, Vikrant V Sahasrabuddhe
exaly

Low-dimensional wide-bandgap semiconductors for UV photodetectors

Nature Reviews Materials, 2023
Ziqing Li, Xiaosheng Fang
exaly

Open reading frames and translational control