Results 101 to 110 of about 70,104,016 (248)

ROER4D Open Research Toolkit - Meta-synthesis conceptual and analytical frameworks

, 2018
The Research on Open Educational Resources for Development (ROER4D) project was a four-year (2013–2017), large-scale networked project which set out to contribute a Global South research perspective on how open educational resources can help to improve ...
Research on Open Educational Resources for Development project
core   +1 more source

Developing a Data Note reporting guideline for qualitative health and social care research datasets (the DeNOTE study): A study protocol

Health Psychology and Behavioral Medicine
Background: Data Note articles describe openly available research datasets. They detail how and why the data were created, with the aim of increasing research transparency and facilitating data reuse.
Hannah A. Long, Elaine Toomey, Fiona Stevenson, Joanna M. Brooks, Andrew J. Stewart, David P. French   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Creating open educational resources

, 2010
Are you interested in creating your own open educational resources? This unit will help you to write a learning unit and provide you with links to various resources for open-learning materials.
Open University
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

OPEN YOUR HEART -- Simon David Hirsbrunner on reasons why media scholars might be reluctant to open their research data

, 2019
Von Simon David Hirsbrunner In the media studies community, open science (OS) is often taken as a synonym for open access publishing. For someone like me, who investigates techno-scientific practice from an epistemological (or ‹STS›) perspective, such a ...
Open Media Studies
core   +1 more source

Afterglow linear polarization signatures from steep GRB jets: Implications for orphan afterglows

Astronomy & Astrophysics
Gamma-ray bursts (GRBs) are the strongest explosions in the Universe, and are powered by initially ultra-relativistic jets. The angular profile of GRB jets encodes important information about their launching and propagation near the central source, and ...
Birenbaum G., Granot J., Beniamini P.
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source