Open research data and methods. National policy and executive plan by the higher education and research community for 2021–2025: Policy component 1 (Open access to research data) and 2 (Open access to research methods and infrastructures) [PDF]
This Policy for Open Access to Research Data and Methods supports the Declaration for Open Science and Research 2020–2025 and its overarching principle that research should be as open as possible and as closed as necessary.
National Coordination of Open Science and Research, AVOTT
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
OPEN SCIENCE AND OPEN MEDIA STUDIES — Questions on a culture in transition by Jeroen Sondervan
Javier Allegue Barros – A Coruña, Spain – https://unsplash.com/photos/C7B-ExXpOIE Von Jeroen Sondervan Open science as a collective term stands for many things; open access to publications, open research data, open source software, research tools, open ...
Open Media Studies
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Offenheit als Grundsatz. Positionspapier zur Entwicklung von Open Research in Berlin
Berlin verfügt über eine einzigartige Wissenschafts- und Kulturlandschaft mit internationaler Strahlkraft. Um diese Position langfristig zu sichern und zu entwickeln, braucht es einen konsequenten Wandel hin zu einer offenen, kooperativen und ...
Landesinitiative Open Research Berlin
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Data-Driven Insights for a Holistic Understanding of Research Culture
Research environments (and their measurement and tracking) are becoming increasingly complex, with rapid Artificial Intelligence (AI) advancements, interdisciplinary collaboration, and global connectivity shaping the way research knowledge is created ...
Ann Campbell +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
New Open Jerusalem Website Online
After five years of work, the Open Jerusalem team is thrilled to announce the opening of its new website. Discover the new Open Jerusalem website!
Open Jerusalem
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Interdisciplinary collaboration for open research: reflections by Graduate Engagement Leads
This case study provides an in-role reflection by the Graduate Engagement Leads for Open Research at the University of York. It uses the methodologies of reflection in practice and reflection-on-the-future to explore the challenges, such as gaps in ...
Katie Vernon +2 more
doaj +1 more source

