Results 101 to 110 of about 8,047,805 (354)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Simulating soil carbon sequestration from long term fertilizer and manure additions under continuous wheat using the DailyDayCent model [PDF]
, 2017 Bangabandhu Fellowship on Science and ICT project, Ministry of Science and Technology, People’s Republic of Bangladesh.
Begum, Khadiza +4 more
core +4 more sources
FAIR and Open Computer Science Research Software [PDF]
arXiv, 2019 In computational science and in computer science, research software is a central asset for research. Computational science is the application of computer science and software engineering principles to solving scientific problems, whereas computer science is the study of computer hardware and software design. The Open Science agenda holds that science
arxiv
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Open Science in the Humanities, or: Open Humanities?
Publications, 2019 Open science refers to both the practices and norms of more open and transparent communication and research in scientific disciplines and the discourse on these practices and norms. There is no such discourse dedicated to the humanities.
Marcel Knöchelmann
doaj +1 more source
, 2019 Genova, Open Access Week 2019, GenOA Week 2019, Genova, Italy, 21 Oct 2019 - 27 Oct 2019; doi:10.5281/ZENODO ...
openaire +3 more sources
FEBS Letters, EarlyView.The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet +4 more
wiley +1 more source
The CombiUgi Project and Closing the Open Science Loop [PDF]
, 2007 This presentation combines 2 blog posts explaining the CombiUgi project and the predicted anti-tumor activity of a virtual library of 68,000 ...
Dan Zaharevitz +3 more
core +2 more sources