Results 131 to 140 of about 8,610,280 (359)

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

Science For All

open access: yesExchanges, 2016
Science is the best method humanity has for understanding the universe and our place in it. However, despite its astonishing achievements, the implementation and communication of science is not without problem.
Liam J. Messin, John C. Meadows
doaj  

Beyond the National Open Science Sphere: Organising the ERUA Open Science Live Meet-Ups

open access: yesLiber Quarterly: The Journal of European Research Libraries
The Open Science Community reaches beyond national borders, which entails the necessity of international exchange to learn from each other and to develop measures jointly. But how to implement formats of exchange? In this report, Maximilian Heber and Dr.
Maximilian Heber, Goran Sekulovski
doaj   +1 more source

Cybersecurity for "Open Science"

open access: yes, 2017
Presentation to the APLU Council on Research, September 9th ...
openaire   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

The Transition to Open Science

open access: yes, 2019
Presentation from Frank Miedema in the Research Assessment panel at the Open Science FAIR 2019 (Porto, 16-17 September 2019).
openaire   +3 more sources

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