Results 131 to 140 of about 8,389,625 (348)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Assessing the Ecosystem for Open Science Advancement in Tanzania
Journal of Information Management and PracticesThis study aims to assess the favourable ecosystem for supporting OS in Tanzania and the factors hindering its adoption and implementation. Employing a cross-sectional research design, the study evaluates the enabling environment for Open Science ...
Paul Muneja +4 more
doaj
Collaborative Research in e-Science and Open Access to Information [PDF]
This contribution examines various aspects of “openness” in research, and seeks to gauge the degree to which contemporary “e-science” practices are congruent with “open science.” Norms and practices of openness are vital for the work of modern scientific
Matthijs den Besten +2 more
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Creating a Diamond Open Access community journal for Seismology and Earthquake Science
, 2021 Martijn van den Ende +7 more
openalex +2 more sources
Advances in Information Technology Improve Open Science Use of Underwater Imagery [PDF]
, 2023 Megan Cromwell +3 more
openalex +1 more source
Women of Faith in Science: the Double Glass Ceiling [PDF]
, 2015 The majority of female pre-service elementary school teachers pursuing licensure is choosing English as their cognate rather than mathematics or science. The reason females are not choosing science as their cognate may be due to the fact that science has
Michael, K. Y.
core +1 more source
, 2019 Genova, Open Access Week 2019, GenOA Week 2019, Genova, Italy, 21 Oct 2019 - 27 Oct 2019; doi:10.5281/ZENODO ...
openaire +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source