Results 141 to 150 of about 8,389,625 (348)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The Moral Schizophrenia in the Fight Against Big Publisha
Dutch Journal of Applied LinguisticsIn this contribution, Ali Al-Hoorie considers open science from a global South perspective and proposes a three-stage roadmap towards scholarship that is truly equitable.
Ali Al-Hoorie
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Open Access – What’s New in the Sciences?
, 2015 Learn about some of the newest open access publications and platforms designed to support and accelerate science research. Join a discussion with librarian liaisons to science departments about how Gettysburg faculty and the library are ...
Scholarly Communications,
core
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
, 2011 Poster presented at the VSMF Symposium held in the Unilever Centre on 2011-01-17Climate Code Foundation - who are we? A non-profit organisation founded in August 2010; our goal is to promote the public understanding of climate science, by increasing the ...
Barnes, Nick, Jones, David
core
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Becoming an effective science teacher at the Department of Curricular Studies, University of Strathclyde [PDF]
, 2009 In an article for the International section, Allan Blake, Colin Smith and Jim McNally from Strathclyde report on the start of a very important EU-funded project, involving 15 countries, which looks at how ‘inquiry-based science’ can be promoted in ...
Blake, Allan +2 more
core