Results 201 to 210 of about 8,389,625 (348)

The economic impact of open science: a scoping review. [PDF]

open access: yesR Soc Open Sci
Tsipouri L   +3 more
europepmc   +1 more source

The Value of Openness in Open Science

open access: yesCanadian Journal of Philosophy
AbstractOpen science is good for both epistemic and social reasons, but in nonobvious ways, it can have detrimental epistemic side effects. Drawing on case studies and the social epistemology of science, I show how practices intended to increase transparency, communication, and information sharing in science can backfire.
openaire   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Open science must include effective results dissemination to study participants. [PDF]

open access: yesPLoS Med
Tai KH   +4 more
europepmc   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Reimagining open science for global health: Epistemic power and the pursuit of health equity. [PDF]

open access: yesPLOS Glob Public Health
Rangel Teixeira A   +7 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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