Results 201 to 210 of about 15,014,800 (402)

Bootstrapping the Open Science culture: The fellowship approach [PDF]

open access: bronze, 1970
Sigrid Fahrer   +3 more
openalex   +1 more source

How to build an Open Science Monitor based on publications? A French perspective [PDF]

open access: yesarXiv
Many countries and institutions are striving to develop tools to monitor their open science policies. Since 2018, with the launch of its National Plan for Open Science, France has been progressively implementing a monitoring framework for its public policy, relying exclusively on reliable, open, and controlled data.
arxiv  

Solving medicine’s data bottleneck: Nightingale Open Science

open access: yesNature Network Boston, 2022
S. Mullainathan, Z. Obermeyer
semanticscholar   +1 more source

Open Science With Openpmd

open access: yes, 2017
{"references": ["A. Huebl et al. openPMD 1.0.0: A meta data standard for particle and mesh based data, technical specification (CC-BY 4.0), November 2015, DOI:10.5281/zenodo.33624", "A. Huebl et al. On the Scalability of Data Reduction Techniques in Current and Upcoming HPC Systems from an Application Perspective, ISC 2017, arXiv:1706.00522", "H ...
Huebl, Axel   +6 more
openaire   +4 more sources

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

open access: yesFEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon   +5 more
wiley   +1 more source

Contextualizing Openness: Situating Open Science.

open access: yes, 2019
Zenodo (2019).
Chan, Leslie   +4 more
openaire   +4 more sources

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

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