Results 221 to 230 of about 8,810,905 (348)

Creating a Diamond Open Access community journal for Seismology and Earthquake Science

, 2021
Martijn van den Ende, Lucile Bruhat, G. J. Funning, Alice‐Agnes Gabriel, Stephen Hicks, Romain Jolivet, Thomas Lecocq, C. D. Rowe   +7 more
openalex   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Artificial Intelligence-Powered Raman Spectroscopy through Open Science and FAIR Principles. [PDF]

ACS Nano
Coca-Lopez N, Alcolea-Rodriguez V, Bañares MA, Brockhauser S, Gorenflot J, Henderson A, Hildebrandt R, Jeliazkova N, Kochev N, Lozano Diz E, Pilat Z, Polli D, Strömert P, Sturm C, Vanna R, Portela R.   +15 more
europepmc   +1 more source

Special Education Researchers’ Knowledge, Attitudes, and Reported Use of Open Science Practices

, 2022
Jesse Irvan Fleming, Sarah Emily Wilson, Daniel R. Espinas, Wilhelmina van Dijk, Bryan G. Cook   +4 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Open science practices among early-career human-computer interaction researchers in the US. [PDF]

PLoS One
Chakravorti T, Gautam S, Rajtmajer S.
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Fostering open science and responsible research practices: A pre-post study. [PDF]

F1000Res
Cenci J, Correa MB, Bouter L, Moher D, Bronkhorst E, Franco MC, Mendes FM, Pereira-Cenci T, Huysmans MC, Cenci MS.   +9 more
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

NASA open science data repository: open science for life in space. [PDF]

Nucleic Acids Res
Gebre SG, Scott RT, Saravia-Butler AM, Lopez DK, Sanders LM, Costes SV.   +5 more
europepmc   +1 more source