Results 231 to 240 of about 15,014,800 (402)

Towards a Post Reductionist Science: The Open Universe

open access: yes, 2009
In this paper I discuss the reality that deductive inference is not the only way we explain in science. I discuss the role of the opportunity for an adaptation in the biosphere and claim that such an opportunity is a 'blind final cause', not an efficient
Kauffman, Stuart
core  

Valuing Open Science

open access: yes, 2019
Österreichischer Bibliothekartag 2019, Graz, Austria, 10 Sep 2019 - 13 Sep 2019; doi:10.5281/ZENODO ...
openaire   +4 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Erste Open Science Policy an einer Universität in Deutschland

open access: yeso-bib. Das offene Bibliotheksjournal, 2022
Markus Putnings, Konstanze Söllner
doaj   +1 more source

From open science to open technology [PDF]

open access: yes, 2014
Este artículo analiza algunos de los aspectos más importantes de los movimientos actuales por la ciencia y la tecnología abiertas y su relación con la producción colaborativa. En el terreno de la ciencia, se tratan especialmente los problemas en torno al
Aibar, Eduard, Dunajcski-Maxigas, Peter
core  

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

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