Results 61 to 70 of about 8,389,625 (348)

Open science prevents mindless science [PDF]

open access: yesBMJ, 2018
Lessons from a case of academic ...
Munafò, Marcus R   +2 more
openaire   +4 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The future(s) of open science [PDF]

open access: yesSocial Studies of Science, 2018
Almost everyone is enthusiastic that ‘open science’ is the wave of the future. Yet when one looks seriously at the flaws in modern science that the movement proposes to remedy, the prospect for improvement in at least four areas are unimpressive. This suggests that the agenda is effectively to re-engineer science along the lines of platform capitalism,
openaire   +2 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Open Sesame: R for Data Science is Open Science

open access: yesIdeas in Ecology and Evolution, 2017
A review of a recent book on data science is framed within the context of open science. I propose that R is a natural bridge between data and open science and a powerful ally in promoting transparent, reproducible science.
Christopher J. Lortie
doaj  

Open Science Framework (OSF)

open access: yesJournal of the Medical Library Association, 2017
The Open Science Framework (OSF) is a free, open source, research workflow web application developed and maintained by the Center for Open Science (COS).
Erin D. Foster, Ariel Deardorff
doaj   +1 more source

Quantum Information Dynamics and Open World Science [PDF]

open access: yes, 2007
One of the fundamental insights of quantum mechanics is that complete knowledge of the state of a quantum system is not possible. Such incomplete knowledge of a physical system is the norm rather than the exception. This is becoming increasingly apparent
Bruza, Peter, Widdows, Dominic
core   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

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