Results 201 to 210 of about 1,279,055 (257)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

SASBDB reaches 5000 data sets: empowering open science and next-generation SAS analysis. [PDF]

open access: yesActa Crystallogr D Struct Biol
Blanchet CE   +4 more
europepmc   +1 more source

A Novel Laboratorial Approach to Evaluate Bacterial Microleakage of Endodontic Sealers. [PDF]

open access: yesCurr Protoc
Monteiro EFTDS   +11 more
europepmc   +1 more source

Protocol for mitochondrial DNA extraction, purity evaluation, and global methylation assessment via LC-MS/MS. [PDF]

open access: yesSTAR Protoc
Chroni A   +5 more
europepmc   +1 more source

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