Results 101 to 110 of about 1,040,059 (296)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Risk Aversion and Trade Union Membership [PDF]

open access: yes
In an open-shop model of trade union membership with heterogeneity in risk attitudes, a worker's relative risk aversion can affect the decision to join a trade union. Furthermore, a shift in risk attitudes can alter collective bargaining outcomes.
Laszlo Goerke, Markus Pannenberg
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Autobiography [PDF]

open access: yes
I was born in Nicosia, Cyprus, on 20 February 1948. My father Antonios was born in the village of Agros, in the Troodos mountains, a village in a valley surrounded by mountains on three sides and with an opening to the south overlooking in the distance ...
Pissarides, Christopher A.
core  

ANALISIS PENGARUH KEBERADAAN MINIMARKET MODERN TERHADAP KELANGSUNGAN USAHA TOKO KELONTONG DI SEKITARNYA (STUDI KASUS KAWASAN SEMARANG BARAT , BANYUMANIK, PEDURUNGAN KOTA SEMARANG) [PDF]

open access: yes, 2015
The purpose of this research is (1) To analyzed levels of profit before and after the traditional shop in surrounding minimarts. (2) To analyzed levels of earnings before and after the traditional shop in surrounding minimarts.
RAHARJO, Reza Haditya   +1 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Bi-Objective, Dynamic, Multiprocessor Open-Shop Scheduling: A Hybrid Scatter Search–Tabu Search Approach

open access: yesAlgorithms
This paper presents a novel, multi-objective scatter search algorithm (MOSS) for a bi-objective, dynamic, multiprocessor open-shop scheduling problem (Bi-DMOSP). The considered objectives are the minimization of the maximum completion time (makespan) and
Tamer F. Abdelmaguid 
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

From new clones to flowers – innovative business models in the Hungarian wine economy

open access: yesBIO Web of Conferences, 2017
Due to the ovestocked Hungarian wine sector wineries often need to find entirely new ways that enable them to increase their market share. These opportunities are determined by the current market potentials, the geographic location and of course the wine
Kismarjai Balázs
doaj   +1 more source

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