Results 41 to 50 of about 1,565,431 (306)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Background Innovation through an open source model has proven to be successful for software development. This success has led many to speculate if open source can be applied to other industries with similar success. We attempt to provide an understanding
Røttingen John-Arne +2 more
doaj +1 more source
Innovation, Imitation and Open Source [PDF]
An extensive empirical literature indicates that, even without formal intellectual property rights, innovators enjoy a variety of first-mover advantages and that `imitation' is itself a costly activity.
Pollock, Rufus
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Impact of Artificial Intelligence on Open-Source Software Development
Open-source software has long been a catalyst for innovation. However, the rise of Artificial Intelligence (AI) is transforming the open source landscape, reshaping code development, project management, and community contributions among other aspects of
Vinod Kumar Ahuja +2 more
doaj +1 more source
How participative is open source hardware? Insights from online repository mining
Open Source Hardware (OSH) is an increasingly viable approach to intellectual property management extending the principles of Open Source Software (OSS) to the domain of physical products.
Jérémy Bonvoisin +3 more
doaj +1 more source
Shanzhai et culture du faire en Chine
This work investigates how digital cultures produce geographic space and how this one influences back technological innovation. It shows how Shenzhen’s maker movement has developed in an inherited manufacturing region, echoing local shanzhai culture ...
Julia Nawrocki
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The role of openness in open collaboration: A focus on open‐source software development projects
Open‐source software development projects are well suited for exploring new ideas and acquiring knowledge from developers outside of the project.
Saerom Lee, Hyunmi Baek, Sehwan Oh
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source

