Results 31 to 40 of about 22,382,567 (255)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Evolutionary success of open source software: An investigation into exogenous drivers [PDF]
, 2007 Copyright @ 2007 EASSTThe “success” of a Free/Libre/Open Source Software (FLOSS) project has often been evaluated through the number of commits made to its configuration management system, number of developers and number of users.
Rank, S +8 more
core +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Usability and open source software. [PDF]
, 2002 Open source communities have successfully developed many pieces of software although most computer users only use proprietary applications. The usability of open source software is often regarded as one reason for this limited distribution. In this paper
Nichols, David M., Twidale, Michael B.
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Empirical studies of open source evolution [PDF]
, 2008 Copyright @ 2008 Springer-VerlagThis chapter presents a sample of empirical studies of Open Source Software (OSS) evolution. According to these studies, the classical results from the studies of proprietary software evoltion, such as Lehman’s laws of ...
Andrea Capiluppi +12 more
core +2 more sources
Cost Optimization Through Open Source Software [PDF]
Technology Innovation Management Review, 2010 The cost of information technology (IT) as a percentage of overall operating and capital expenditures is growing as companies modernize their operations and as IT becomes an increasingly indispensable part of company resources.
Mark VonFange, Dru Lavigne
doaj
Big data of open source ecosystem for intelligent software development
大数据, 2021 The open source software development process contains a lot of valuable data, which is huge in scale, fragmented, and rapidly expanding. Aimming to the characteristics, the big data structure of open source ecosystem of software engineering was studied ...
Yang ZHANG +4 more
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source