Results 61 to 70 of about 3,361,942 (285)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Sosialisasi Pemanfaatan Software Open Source di SMK Muhammadiyah 1 Surakarta
Warta LPM, 2017 Embrace of open source software (OSS) has not been widespread although users of OSS will gain a lot of benefits and the society and the nation will get many advantages.
Husni Thamrin +2 more
doaj +1 more source
Software Architecture Degradation in Open Source Software: A Systematic Literature Review
IEEE Access, 2020 Software architecture (SA) has a prominent role in all stages of system development. Given the persistent evolution of software systems over time, SA tends to be eroded or degraded. Such phenomenon is called architectural degradation.
Ahmed Baabad +3 more
doaj +1 more source
Open Source Software Acquisition
, 2005 Lately we have seen a growing interest from both public and private organisations to adopt OpenSource Software (OSS), not only for a few, specific applications but also on a more general levelthroughout the organisation. As a consequence, the organisations' decisions on adoption of OSS arebecoming increasingly more important and complex.
Holck, Jesper +2 more
openaire +2 more sources
Agent-based Simulation of Open Source Software Evolution [PDF]
, 2006 We present an agent-based simulation model of open source software (OSS). To our knowledge, this is the first model of OSS evolution that includes four significant factors: productivity limited by the complexity of software modules, the software's ...
Capiluppi, A. +2 more
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Cybrarians Journal, 2014 The study aimed to identify open source software available for libraries and its various types, especially open source systems for library management, in addition to other software that can be used by specialists in the field of libraries.
Ahmed Khafaga
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Exploiting Open-source Projects to Study Software Design
Informatics in Education, 2007 This article presents an approach to using open-source tools and open-source projects to add realistic and practical examples to a course on software design in a professional master's program of software engineering. Students are encouraged to use object-
Christopher P. FUHRMAN
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source