Results 81 to 90 of about 1,658,706 (311)

The costs and benefits of providing open space in cities [PDF]

open access: yes
We use the monocentric model of a city to derive a simple cost-benefit rule for the optimal provision of open space. Although many researchers have investigated the value of open space in cities, few of them have compared it to the costs of providing ...
Jan Rouwendal   +1 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Exhibition announcement: 2 American Artists, Open Space, Victoria, British Columbia, 1985, recto

open access: yes, 1985
Printed exhibition announcement for 2 American Artists at Open Space Gallery, British Columbia, Vancouver, Canada, in May and June, 1985.

core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The Trade-off between Private Lots and Public Open Space in Subdivisions at the Urban-Rural Fringe [PDF]

open access: yes
In many communities on the urban–rural fringe, subdivisions are subject to “clustering” rules, in which houses must be located on a portion of the total land area and the remainder of the land is left as open space.
McConnell, Virginia D.   +2 more
core  

The Peregrine Ion Trap Mass Spectrometer (PITMS) Investigation Development and Preflight Planning

open access: yesThe Planetary Science Journal
The Peregrine Ion Trap Mass Spectrometer (PITMS) is a mass spectrometer instrument that operated during the Astrobotic Peregrine Mission-1 as part of the NASA Commercial Lunar Payload Services initiative.
Barbara A. Cohen   +36 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Exhibition announcement: 2 American Artists, Open Space, Victoria, British Columbia, 1985

open access: yes, 1985
Printed exhibition announcement for 2 American Artists at Open Space Gallery, British Columbia, Vancouver, Canada, in May and June, 1985.

core  

IMF dependence of the open-closed field line boundary in Saturn's ionosphere, and its relation to the UV auroral oval observed by the Hubble Space Telescope [PDF]

open access: yes, 2007
We study the dependence of Saturn's magnetospheric magnetic field structure on the interplanetary magnetic field (IMF), together with the corresponding variations of the open-closed field line boundary in the ionosphere.
Badman, S. V.   +13 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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