Results 71 to 80 of about 4,056,472 (267)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Frost heave experiments on saturated sandstone under unidirectional freezing conditions in an open system and coupled THM frost heave model

open access: yesYantu gongcheng xuebao, 2019
To study the frost heave of rocks in cold regions under temperature gradient with water supply, the frost heave experiments on saturated sandstone under unidirectional freezing conditions are conducted in an open system.
LÜ Zhi-tao 1,2, XIA Cai-chu 1,2, LI Qiang 1,2, WANG Yue-song 1,2
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Long-range navigation for resource-constrained planetary rovers using angle of arrival

open access: yesMechanical Engineering Journal, 2015
This study presents a new navigation system consisting of a resource-constrained rover and landers for planetary long-range exploration. During the exploration, they communicate with each other using radio and the rover receives signals from the landers ...
Takayuki ISHIDA   +5 more
doaj   +1 more source

On the verification of open distributed systems

open access: yesProceedings of the 1998 ACM symposium on Applied Computing - SAC '98, 1998
A logic and proof system is introduced for specifying and proving properties of open distributed systems. Key problems that are addressed include the verification of process networks with a changing interconnection structure, and where new processes can be continuously spawned. To demonstrate the results in a realistic setting we consider a core
Mads Dam, Lars-Åke Fredlund
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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