Results 81 to 90 of about 4,329,795 (301)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

A sense of coherence through work : Mildly developmentally disabled person's experiences of the open work activity

, 2016
The open work activity is a social service that the state and municipalities offer according to Finnish laws. The workplace can for example be a school kitchen or a store, the work assignments and work schedules are applied according to the client’s ...
Hänninen, Milla
core   +1 more source

The Role of Higher Education in Shaping Essential Personality Traits for Achieving Success in Entrepreneurship in Spain

Behavioral Sciences
Research on university education and its role in developing personality traits essential to achieving success in entrepreneurship is required because of the significance of entrepreneurship for advancements in the economic, social, technological, and ...
Joaquín R. Puerta Gómez, Pedro Aceituno-Aceituno, Concepción Burgos García, Aitana González-Ortiz-de-Zárate   +3 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Pousseur’s Scambi (1957), and the new problematics of the open work

, 2005
I begin with an irony. Pousseur’s Scambi (1957), cited as an exemplum in Umberto Eco’s famous essay on the ‘open’ work (Eco 1989) has, as a result, been reified as a historical mo(nu)ment.
Ayrey, Craig L.
core  

Understanding Attitudes and Perceptions Towards Blood Donation in Greece: An Analysis Aligned with the Health Belief Model

European Psychiatry
Introduction This study explores attitudes toward blood donation in Greece, where maintaining an adequate supply is challenging. Using the Health Belief Model, we examine factors like perceived severity, vulnerability, and self-efficacy. Objectives The
M. Theodoratou, D. Papandrea, I. V. Papathanasiou, P. Andriopoulou, C. Dafogianni, I. Farmakopoulou   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Fallout: the psychosocial harms of negative military discharge experiences

Frontiers in Psychology
Military discharge marks a pivotal life transition, often resulting in loss of identity, purpose, and belonging. Negative discharge experiences are further associated with feelings of institutional betrayal. This study explored which aspects of discharge
Cameron Grant, Cameron Grant, Cameron Grant, Lydia Woodyatt, Lydia Woodyatt, Henry Bowen, Henry Bowen, Jonathan Lane   +7 more
doaj   +1 more source

Financing of Works with Public Opening

Journal of Business and Econometrics Studies
Public works financing faces a critical challenge: while traditional projects meet deadlines and budgets by 75-80%, those with public-private partnerships (PPPs) achieve 90-95% efficiency (MEF-Perú, 2023). However, a study of 37 cases in the US reveals that 40% of PPPs generate disputes due to regulatory failures or financial management ...
openaire   +1 more source