Results 121 to 130 of about 87,152,972 (291)
Stressful life events and openness to experience: Relevance to depression. [PDF]
J Affect Disord, 2021 Chiappelli J +5 more
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
[Clipping: Going For It - Experience Weekend Graduates Who Are Making A Difference: Mary Franklin]
, 1988 Copy of The Experience Weekend newspaper pages 5 and 6 of story "Going For It - Experience Weekend Graduates Who Are Making A Difference: Mary Franklin", Wednesday, March 30 ...
The Experience Weekend
core
Perceived usefulness of, engagement with, and effectiveness of virtual reality environments in learning industrial operations: the moderating role of openness to experience. [PDF]
Virtual Real, 2023 Wong EY, Hui RT, Kong H.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Financial openness and macroeconomic volatility [PDF]
We analyze the implications of financial openness to macroeconomic volatility in a small open economy. Major macroeconomic aggregates show non-monotonic volatility patterns with respect to the degree of financial openness in the model without domestic ...
von Hagen, Jürgen, Zhang, Haiping
core
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
TRADE BARRIERS, OPENNESS, AND ECONOMIC GROWTH [PDF]
Using a long dataset on openness and productivity this paper tests the influence of openness on TFP growth and per capita growth since 1870 for 16 industrialized countries.
Jakob Madsen
core
Benevolent Leadership and Team Creative Performance: Creative Self-Efficacy and Openness to Experience. [PDF]
Front Psychol, 2021 Xia Z, Yu H, Yang F.
europepmc +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source