Results 131 to 140 of about 621,602 (294)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

A study on optimism as a psychological strength in nurses through a prospective study from the outbreak of the COVID-19 pandemic to two years later

Brain, Behavior, & Immunity - Health
Aims and objectives: This study analyzes, in nurses, the influence of openness to experience and hardiness (assessed at baseline and one year after the COVID-19 pandemic respectively) on the development of optimism (assessed two years after the COVID-19 ...
Fernanda Gil-Almagro, Fernando J. García-Hedrera, F. Javier Carmona-Monge, Cecilia Peñacoba-Puente   +3 more
doaj   +1 more source

Buffer or boost? the role of openness to experience and knowledge sharing in the relationship between team cognitive diversity and members' innovative work behavior. [PDF]

Curr Psychol, 2022
Cui G, Wang F, Zhang Y.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Openness and growth: what have we learned? [PDF]

This paper discusses recent evidence regarding the existence of a cross-country empirical relationship between openness to international trade and economic growth.
Francisco Rodriguez
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Default mode network functional connectivity negatively associated with trait openness to experience. [PDF]

Soc Cogn Affect Neurosci, 2021
Marstrand-Joergensen MR, Madsen MK, Stenbæk DS, Ozenne B, Jensen PS, Frokjaer VG, Knudsen GM, Fisher PM.   +7 more
europepmc   +1 more source

Managing Openness and Volatility: The Role of Export Diversification [PDF]

As developing countries look to embrace an outward-oriented growth strategy, some may be concerned about the possibility that increased openness will be accompanied by increased volatility.
Haddad, Mona, Lim, Jamus Jerome, Saborowski, Christian   +2 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Science vs. Conspiracy Theory about COVID-19: Need for Cognition and Openness to Experience Increased Belief in Conspiracy-Theoretical Postings on Social Media. [PDF]

Behav Sci (Basel), 2022
Ozimek P, Nettersheim M, Rohmann E, Bierhoff HW.   +3 more
europepmc   +1 more source