Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
LABOR ADJUSTMENT DYNAMICS: AN APPLICATION OF SYSTEM GMM [PDF]
This paper analyzes the dynamics of the Portuguese labor market using micro data: implications of adjustment costs to input factor adjustment throughout the business cycle are discussed; the current situation of the Portuguese labor market is reviewed ...
Pedro M. Esperança
core
Assessment of methadone maintenance therapy implementation and perceived barriers to treatment participation: A mixed-methods study. [PDF]
Medicine (Baltimore)Nhu DD +14 more
europepmc +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Response to the letter to the editor: Risk factors for cage subsidence following anterior-posterior spinal fixation in osteoporotic vertebral fractures: a multicenter retrospective study. [PDF]
Asian Spine JKinoshita Y +17 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Seasonal Adjustment Methods : An Application to the Turkish Monetary Aggregates [PDF]
Seasonality can be defined as a pattern of a time series, which repeats at regular intervals every year. Seasonal fluctuations in data make it difficult to analyse whether changes in data for a given period reflect important increases or decreases in the
Beyza Pinar Ural, Oguz Atuk
core
Urban Climate Risk Governance and Corporate Energy Intensity: Evidence From China's Climate Adaptation City Pilots. [PDF]
Ann N Y Acad SciLiang S, Long Y, Xiao J, Lu X, Chen D.
europepmc +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Asymmetric Adjustment Costs and The Dynamics of Housing Supply [PDF]
This paper considers the potential effects of asymmetric adjustment costs on the dynamics of housing supply. The model in Section 2 provides explicit microfoundations for the divergence between long and short run supply elasticities and also predicts ...
Kenny, Geoff
core