vNOTES Versus Laparoscopic Lateral Suspension for Advanced Pelvic Organ Prolapse: A Single-Center, Single-Surgeon Retrospective Cohort Study. [PDF]
Sarıkaya S +6 more
europepmc +1 more source
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Time Matters: One Year Later, Rethinking Anesthesia Time. [PDF]
Ridgell L, López-Gil JF.
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara +3 more
wiley +1 more source
Preoperative prognostic nutritional index and in-hospital mortality in neonates undergoing cardiac surgery for congenital heart disease: a single-center retrospective study. [PDF]
Zhang H, Dong H, Fan T, Liang W.
europepmc +1 more source
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source
Reply: When Discrimination Transports but the Operating Point Does Not: AI-ECG for Left Ventricular Dysfunction. [PDF]
Lee HS, Kwon JM, Kang S, Rhee TM, Lee H.
europepmc +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Timing of surgical intervention following traumatic femoral fractures in Northern Tanzania: a hospital-based retrospective cohort study. [PDF]
Olotu FI, Mboya IB, Temu RJ, Mahande MJ.
europepmc +1 more source

