Results 81 to 90 of about 1,286,244 (294)

Doppler‐Derived Renal Venous Stasis Index in the Prognosis of Right Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Persistent congestion with deteriorating renal function is an important cause of adverse outcomes in heart failure. We aimed to characterize new approaches to evaluate renal congestion using Doppler ultrasonography.
Faeq Husain‐Syed, Horst‐Walter Birk, Claudio Ronco, Tanja Schörmann, Khodr Tello, Manuel J. Richter, Jochen Wilhelm, Natascha Sommer, Ewout Steyerberg, Pascal Bauer, Hans‐Dieter Walmrath, Werner Seeger, Peter A. McCullough, Henning Gall, H. Ardeschir Ghofrani   +14 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Carbon dioxide angiography during peripheral angioplasty procedures significantly reduces the risk of contrast-induced nephropathy in patients with chronic kidney disease

CVIR Endovascular, 2020
Background Iodinated contrast media are amongst the most frequently prescribed medications, however, their use is not without complications. With contrast-induced nephropathy constituting a major concern, alternative non-iodine based approaches have been
Athanasios Diamantopoulos, Lorenzo Patrone, Serafino Santonocito, Iakovos Theodoulou, Shazhad Ilyas, Renato Dourado, David Game, Narayan Karunanithy, Sanjay Patel, Hany Zayed, Konstantinos Katsanos   +10 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Solutions of some problems in applied mathematics using MACSYMA [PDF]

Various Symbolic Manipulation Programs (SMP) were tested to check the functioning of their commands and suitability under various operating systems. Support systems for SMP were found to be relatively better than the one for MACSYMA.
Lam, Maria, Punjabi, Alkesh
core   +1 more source

Multi-operator colligations and multivariate characteristic functions [PDF]

Analysis and Mathematical Physics, 2011
In the spectral theory of non-self-adjoint operators there is a well-known operation of product of operator colligations. Many similar operations appear in the theory of infinite-dimensional groups as multiplications of double cosets. We construct characteristic functions for such double cosets and get semigroups of matrix-valued functions in matrix ...
openaire   +3 more sources

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Functions which operate on characteristic functions [PDF]

Pacific Journal of Mathematics, 1965
Konheim, Alan G., Weiss, Benjamin
openaire   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source