Results 81 to 90 of about 469,931 (305)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Condition monitoring of gearboxes using acoustic emission [PDF]
, 2010 Acoustic emission (AE) is one of many technologies for health monitoring and diagnosis of rotating machines such as gearboxes. Although significant research has been undertaken in understanding the potential of AE in monitoring gearboxes this has been ...
Eftekharnejad, Babak
core
Establishment of the mathematical model for diagnosing the engine valve faults by genetic programming [PDF]
, 2006 Available machine fault diagnostic methods show unsatisfactory performances on both on-line and intelligent analyses because their operations involve intensive calculations and are labour intensive.
Yang, Wen-xian
core +1 more source
International Journal of ThermofluidsA braking system is a fundamental part of any vehicle and represents a very complex topic due to its highly coupled phenomena taking place at once during its functioning.
F. Orlandi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A change-detection algorithm for short-circuit fault detection in closed-loop AC drives [PDF]
, 2013 This paper deals with an on-line method for turn-to-turn short-circuit fault detection in low-voltage permanent-magnet synchronous machine drives. Due to the closed-loop control, the fault effects are reflected in the voltage.
Johan Gyselinck +10 more
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Broken Bar Fault Detection in IM Operating Under No-Load Condition
Advances in Electrical and Computer Engineering, 2016 This paper presents a novel method for broken rotor bar detection in a squirrel-cage induction motor (IM). The proposed method applies a single-phase AC voltage as a test signal on motor terminals, resulting in a stator backward-rotating magnetic field.
RELJIC, D. +3 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source