Results 41 to 50 of about 1,950,867 (244)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Endodontic microsurgery: An overview

Dentistry and Medical Research, 2015
The concurrent development of better techniques has resulted in greater understanding of the apical anatomy, greater treatment success, and a more favorable patient response. These developments marked the beginning of the endodontic microsurgery era that
Sumangali Ananad, E Soujanya, Ananda Raju, Aravelli Swathi   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Utilization of magnification devices in Vietnam’s dental practice and education: an online survey

BMC Oral Health
Background Advancements in dental technology have enhanced diagnostic and treatment tools, with magnification devices improving clinical precision and ergonomics.
Minh-Hieu Nguyen Tran, Anh Huynh Bui, Lan-Anh Hoang Le, Thuy-Trang Thi Huynh, Phuong-Doan Phan, Thuan-Loc Tran, Nguyen-Tra-Mi Le, Thu-Tra Nguyen, Hoang-Vinh Le, Dai-Phong Lam, Quoc-Viet Lam, Tran-Lan-Khue Pham, An-Tran Pham, Van-Khoa Pham   +13 more
doaj   +1 more source

Recognition versus Disclosure: An Investigation of the Impact on Equity Risk Using UK Operating Lease Disclosures [PDF]

, 2000
This study examines the equivalency of accounting recognition versus disclosure. OLS regression analysis is used to determine whether there is an association between equity risk and an adjustment to financial risk for off-balance sheet operating leases ...
Alan Goodacre, Sarah Thomson, Vivien Beattie, Goodacre, Alan, Thomson, Sarah Jane, Thomson, S., Goodacre, A., Beattie, Vivien, Smith, Sarah Jane, Beattie, V.   +9 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Using latex film sheet in the fresh cadaveric cow brain for the evaluating brain protection

Archives of Clinical and Experimental Surgery, 2018
Objective: Assessment of latex film sheet usage to protect the brain tissue against the harmful mechanical effects of metal microsurgical instruments while doing neurosurgical interventions has been the aim of this experimental study.
Ahmet Gokyar, Cengiz Cokluk
doaj   +1 more source

Operating microscope: diffusion and limits [PDF]

, 2012
Objective: To define the diffusion and characteristics of the operating microscope (OM) and magnifying tools among expert endodontists (belonging to the Società Italiana di Endodonzia [SIE]) in Italy and in a sample of general dentists of Naples ...
Maddaloni, Glenda, AMATO, Massimo, RENGO, SANDRO, Glenda Maddaloni, RICCITIELLO, FRANCESCO, Sandro Rengo, Colomba D’Ambrosio, Francesco Riccitiello, SIMEONE, MICHELE, D’Ambrosio, Colomba, Michele Simeone   +10 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source