Results 51 to 60 of about 2,638,696 (303)
Algorithms and probabilistic models of parameters of operation of in-plant power supply
Известия высших учебных заведений: Проблемы энергетики, 2021 PURPOSE. To address the problems of the functioning of the SES. To develop algorithms for evaluating the parameters of the efficiency of the functioning of the systems of intra-plant power supply.
E. I. Gracheva +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Analysis of shunting locomotive operating modes when performing traction tasks
Збірник наукових праць Державного університету інфраструктури та технологій: серія "Транспортні системи і технології", 2023 The paper considers the modes of operation of shunting diesel locomotives ČME3 when performing traction tasks at the service areas of the locomotive depot Koziatyn. A mathematical model of train movement with a ČME3 diesel locomotive has been developed,
I. Kostenko +4 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
THE STRAIN-STRESS STATE INVESTIGATION OF STRUCTURAL UNITS OF THE BALLAST PRISM BY TYPE SP3-5/UA
Nauka ta progres transportu, 2010 In the article the results of analytical and experimental studies of the stressed-and-strained state of load-bearing elements of structure of ballast prism planner of SPZ-5/UA are presented.
S. A. Kostrytsia, B. M. Tovt
doaj
Features of Modeling the Operating Modes of Outdoor Lighting Lines
Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2022 The necessity of modeling the operating modes of outdoor lighting lines with a voltage of 0.23/0.4 kV is substantiated. The choice of the optimal configuration of the lighting line while ensuring the standardized values of illumination and brightness on ...
V. N. Kalechyts
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source