Results 81 to 90 of about 5,929,784 (390)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Virus and viral components transmitted through surgical smoke; a silent danger in operating room: a systematic review

BMC Surgery
Background During surgical procedures, heat-generating devices are widely used producing surgical smoke (SS). Since the SS can transmit infectious viruses, this systematic review was designed to investigate the potential viruses transmitted through SS ...
Bahareh Mahdood, Amirmohammad Merajikhah, Mina Mirzaiee, Maryam Bastami, Sara Banoueizadeh   +4 more
doaj   +1 more source

Gate-tunable coherent perfect absorption of terahertz radiation in graphene

, 2014
Perfect absorption of radiation in a graphene sheet may play a pivotal role in the realization of technologically relevant optoelectronic devices. In particular, perfect absorption of radiation in the terahertz (THz) spectral range would tremendously ...
Adam, Shaffique, Chong, Y. D., Liu, Fangli, Polini, Marco   +3 more
core   +1 more source

Prevention of pressure injury in the operating room: Heels operating room pressure injury trial

International Wound Journal, 2020
The objective was to evaluate the efficacy of multi‐layered silicone foam (intervention) compared with transparent polyurethane film (control) in preventing heel pressure injuries caused by surgical positioning of individuals undergoing elective surgery.
T. Eberhardt, Suzinara Beatriz Soares de Lima, Rhea Silvia de Avila Soares, L. Silveira, Bruna Rossarola Pozzebon, Cassia Ribeiro Reis, Karla Priscilla Paulino Dos Santos, P. Alves   +7 more
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Efficacy and safety of Ciprofol for procedural sedation and anesthesia in non-operating room settings.

Journal of clinical anesthesia, 2023
Jing Zhong, Jinlin Zhang, Yuan-ming Fan, Ming Zhu, Xining Zhao, Zhiyi Zuo, Xiushi Zhou, C. Miao   +7 more
semanticscholar   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Research on the application effect of inter-professional training program for newly enrolled medical staff in operating room based on digital information technology

BMC Medical Education
Background The operating room environment demands high levels of teamwork and interprofessional collaboration, yet current training programs often lack sufficient opportunities to develop these essential skills.
Manhong Zhang, Wenjun Wang
doaj   +1 more source

Quiet in the Operating Room! Team STEPPS and OR Distractions [PDF]

, 2017
Background and Objective: From the moment that a patient enters the operating room to the time that they are brought to the post anesthesia care unit, a distraction has the potential to lead to an adverse outcome for the patient.
Brinson, MD, Zabecca S., Cacciatore, RN, Susan, Farmer, RN, Rose, Johnson, MD, MPH, Adam P., Leonard, CRNA, Tesa, Palazzo, MD, Francesco, Sammut, RN, Paul, Sanchez, RN, Maritza, Weikel, RN, Lorie   +8 more
core   +1 more source