Results 41 to 50 of about 119,265 (294)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Are the urology operating room personnel aware about the ionizing radiation?

International Brazilian Journal of Urology, 2015
Purpose: We assessed and evaluated attitudes and knowledge regarding ionizing radiation of urology surgery room staff. Materials and Methods: A questionnaire was sent by e-mail to urology surgery room personnel in Turkey, between June and August 2013 ...
Adem Tok, Alparslan Akbas, Nimet Aytan, Tamer Aliskan, Izzet Cicekbilek, Mehmet Kaba, Abdulkadir Tepeler   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Use of the nursing intervention classification for identifying the workload of a nursing team in a surgical center

Revista Latino-Americana de Enfermagem, 2015
Objective: to analyze the distribution of nursing professionals' workloads, according to the Nursing Intervention Classification (NIC), during the transoperative period at a surgical center specializing in oncology.Methods: this was an observational and ...
João Francisco Possari, Raquel Rapone Gaidzinski, Antônio Fernandes Costa Lima, Fernanda Maria Togeiro Fugulin, Tracy Heather Herdman   +4 more
doaj   +1 more source

Control of Methicillin-Resistant Staphylococcus aureus Strains Associated With a Hospital Outbreak Involving Contamination From Anesthesia Equipment Using UV-C

Frontiers in Microbiology, 2020
Methicillin-resistant Staphylococcus aureus (MRSA) is considered an opportunistic pathogen in humans and is mainly associated with healthcare-associated infections (HCAIs).
Sara A. Ochoa, Ariadnna Cruz-Córdova, Jetsi Mancilla-Rojano, Jetsi Mancilla-Rojano, Gerardo Escalona-Venegas, Veronica Esteban-Kenel, Isabel Franco-Hernández, Israel Parra-Ortega, José Arellano-Galindo, Rigoberto Hernández-Castro, Citlalli F. Perez-López, Daniela De la Rosa-Zamboni, Juan Xicohtencatl-Cortes   +12 more
doaj   +1 more source

Talking about routines in the field: the emergence of organizational capabilities in a new cellular phone network company [PDF]

, 1997
No abstract ...
Narduzzo, Alessandro, Rocco, Elena, Warglien, Massimo   +2 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Metaphorical Perceptions of Operating Room Staff Towards the Concept of Pressure Ulcer: A Qualitative Study

Journal of Nursology
Objective: To explain the perceptions of the operating room staff about pressure ulcers through metaphors. Methods: A descriptive qualitative research design was used. In the study, it was aimed to reach the entire universe, not choosing a sample.
Fatma Eti Aslan, Betül İlbey Koç, Goknur Parlak, Dilay Hacıdursunoğlu Erbaş   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Investigation of supplement products preferred by healthcare professionals during COVID-19 pandemic process

Journal of Contemporary Medicine, 2023
Objective: Various products are used to strengthen immunity in prevention and treatment during the COVID-19 pandemic affecting the whole world, which has no cure yet, and the vaccine has just been used.
Gülsen Keskin, Oya Kale
doaj   +1 more source