Results 91 to 100 of about 4,219,504 (325)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
ROSIDS23: Network intrusion detection dataset for robot operating system. [PDF]
Data Brief, 2023 Değirmenci E +3 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Вестник Дагестанского государственного технического университета: Технические наукиObjective. The article examines the influence of the “man-machine-environment” system on the reliability of automated systems of internal affairs bodies of the Russian Federation.Method.
A. I. Yangirov +4 more
doaj +1 more source
Satellite freeze forecast system. Operating/troubleshooting manual [PDF]
Examples of operational procedures are given to assist users of the satellites freeze forecasting system (SFFS) in logging in on to the computer, executing the programs in the menu, logging off the computer, and setting up the automatic system ...
Martsolf, J. D.
core +1 more source
Dynamic Geospatial Spectrum Modelling: Taxonomy, Options and Consequences [PDF]
, 2010 Much of the research in Dynamic Spectrum Access (DSA) has focused on opportunistic access in the temporal domain. While this has been quite useful in establishing the technical feasibility of DSA systems, it has missed large sections of the overall DSA ...
Al-Tamaimi, Mohammed +2 more
core +5 more sources
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
IBM PC/IX operating system evaluation plan [PDF]
An evaluation plan for the IBM PC/IX Operating System designed for IBM PC/XT computers is discussed. The evaluation plan covers the areas of performance measurement and evaluation, software facilities available, man-machine interface considerations ...
Dominick, Wayne D. +3 more
core +1 more source
RPI64Box: A portable 3-tiered LAMP stack in a 64-bit Operating System environment [PDF]
, 2022 Riyad Dhuny, NAWAZ MOHAMUDALLY
openalex +1 more source