Results 111 to 120 of about 3,121,689 (316)
Chemical Processing Department Monthly Report: 1962-05
, 1962 This report, for May 1962 from the Chemical Processing Department at HAPO, discusses the following: Production operation; Purex and Redox operation; Finished products operation; maintenance; Financial operations; facilities engineering; research ...
Hanford Atomic Products Operation. Chemical Processing Department.
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
, 1964 This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Congress For International Co-operation And Disarmament
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Chemical Processing Department Monthly Report: 1965-08
, 1965 This report, from the Chemical Processing Department at HAPO, August 1965, discusses the following: Production Operation; Purex and Redox Operation; Finished Products Operation; Maintenance; Financial Operations; facilities engineering; research; and ...
Hanford Atomic Products Operation. Chemical Processing Department.
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Chemical Processing Department Monthly Report: 1960-06
, 1960 This report for June 1960, from the Chemical Processing Department at HAPO, discusses the following: Production operation; Purex and Redox operation; Finished products operation; maintenance: Financial operations; facilities engineering; research; and ...
Hanford Atomic Products Operation. Chemical Processing Department.
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Chemical Processing Department Monthly Report: 1965-09
, 1965 This report, from the Chemical Processing Department at HAPO, September 1965, discusses the following: Production Operation; Purex and Redox Operation; Finished Products Operation; Maintenance; Financial Operations; facilities engineering; research; and ...
Hanford Atomic Products Operation. Chemical Processing Department.
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source