Results 101 to 110 of about 3,703,583 (316)
Reliability and Quality of Complex Systems
Надежность и качество сложных системBackground. It is shown that the mesodiagnostic apparatus allows solving problems not only of express assessment of the condition of materials and products, taking into account their current damage, but also to carry out resource and operational ...
A.A. Barzov +5 more
doaj +1 more source
THE HEAT OPERATOR OF A TRANSVERSALLY ELLIPTIC OPERATOR [PDF]
JP Journal of Geometry and Topology, 2017 Let $G$ be a connected compact Lie group. We study the heat operator of a $G$-transversally elliptic operator. After we review the spectral properties of a $G$-transversally elliptic operator, we define the character, that is a distribution on $G$ generalizing the trace of the heat operator to the $G$-equivariant case.
openaire +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Chemical Processing Department Monthly Report: 1963-06
, 1963 This report, from the Chemical Processing Department at HAPO for June 1963, discusses the following: Production operation; Purex and Redox operation; Finished products operation; maintenance; Financial operations, facilities engineering; research; and ...
Hanford Atomic Products Operation. Chemical Processing Department.
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Chemical Processing Department Monthly Report: 1962-04
, 1962 This report, from the Chemical Processing Department at HAPO, for April 1962 discusses the following: Production operation; Purex and Redox operation; finished products operation; maintenance; financial operations; facilities engineering; research ...
Hanford Atomic Products Operation. Chemical Processing Department.
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Chemical Processing Department Monthly Report: 1963-02
, 1963 This report, for February 1963 from the Chemical Processing Department at HAPO, discusses the following: Production operation; Purex and Redox operation; Finished products operation; maintenance; Financial operations; facilities engineering; research ...
Hanford Atomic Products Operation. Chemical Processing Department.
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source