Results 61 to 70 of about 1,937,847 (297)

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

ASPECTS REGARDING THE USE OF UAV IN INTELLIGENCE OPERATIONS RECONNAISSANCE AND SURVEILLANCE [PDF]

open access: yesJournal of Defense Resources Management, 2019
This article presents the evolution of the instruments and means used in reconnaissance and surveillance, with the purpose of delivering the information needed for planning the military operations. Acquirement of the information was and still is the most
Grițco Vitalie
doaj  

Hazards That Can Affect CNC Machine Tools during Operation—An AHP Approach

open access: yesSafety, 2020
CNC (computer numerically controlled) machine tools are highly advanced technological systems, used to machine parts by means of metal cutting processes.
Sever-Gabriel Racz   +2 more
doaj   +1 more source

Operator Calculus of Quantized Operator [PDF]

open access: yesProgress of Theoretical Physics, 1952
The notational ambiguities in Feynman's calculus are all remedied here by setting a more natural foundation of the ordered exponential operators, which will be called briefly "expansional" operators in this paper. The essential point to be stressed is that the pure exponential opErator is merely a special case of the more wider class of operators, i.e.,
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Isospectral Operators [PDF]

open access: yesCommunications in Mathematics and Statistics, 2014
Corrections are made in this ...
Chen, Mu-Fa, Zhang, Xu
openaire   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Operation of Building Objects Based on the Informational Model

open access: yesЦифровая трансформация, 2019
This article reviews and assesses the possibilities and features of the application of information modeling technology at such an important stage of work as the operation of a building. At present, it becomes more and more obvious that the most promising
E. V. Borsuk, A. S. Davidovich
doaj   +1 more source

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