Results 61 to 70 of about 3,844,707 (316)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Chemical Processing Department Monthly Report: 1963-04

open access: yes, 1963
This report, from the Chemical Processing Department at HAPO for April 1963, discusses the following: Production operation; Purex and Redox operation; Finished products operation; maintenance; Financial operations, facilities engineering; research ...
Hanford Atomic Products Operation. Chemical Processing Department.
core   +1 more source

Impact of the technical condition of main pumps on fuel consumption in a hydraulic excavator

open access: yesГорные науки и технологии
During the operation of hydraulic excavators, the technical condition of pumps deteriorates due to wear, leading to increased internal clearances, fluid leakage, a reduction in volumetric efficiency, and higher energy losses, ultimately resulting in ...
Maxim G. Rakhutin   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Chemical Processing Department Monthly Report: 1964-11

open access: yes, 1964
This report for November 1964, from the Chemical Processing Department at HAPO, discusses the following: Production operation; Purex and Redox operation; Finished products operation; maintenance; Financial operations; facilities engineering; research ...
Hanford Atomic Products Operation. Chemical Processing Department.
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Chemical Processing Department Monthly Report: 1960-10

open access: yes, 1960
This report, from the Chemical Processing Department at HAPO for October 1960, discusses the following: Production operation; Purex and Redox operation; Finished products operation; maintenance; Financial operations, facilities engineering; research ...
Hanford Atomic Products Operation. Chemical Processing Department.
core   +1 more source

Improved Symbiotic Organisms Search Algorithm for Optimal Operation of Active Distribution Systems Incorporating Renewables and Emerging Data‐Center Resources

open access: yesEnergy Science & Engineering, 2021
The optimal operation analysis plays an important role in estimating the expected return of investment for power systems. However, this work could be highly challenging under the context of active distribution network, where a variety of renewable energy
Bo Zeng, Hao Xu, Wenshi Wang, Lei Zhu
doaj   +1 more source

Operators Approximable by Hypercyclic Operators [PDF]

open access: yesMathematical Proceedings of the Royal Irish Academy, 2015
We show that operators on a separable infinite dimensional Banach space $X$ of the form $I +S$, where $S$ is an operator with dense generalised kernel, must lie in the norm closure of the hypercyclic operators on $X$, in fact in the closure of the mixing operators.
openaire   +4 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Home - About - Disclaimer - Privacy