Results 41 to 50 of about 443,693 (235)

A Method for Determining the Usability Potential of Ship Steam Boilers

Polish Maritime Research, 2016
Ship large-power steam boiler may serve as an example of complex critical technical system. A basis for rational control of operation of such system is knowledge on its capability of fulfilling the tasks to which it was intended.
Muślewski Łukasz, Pająk Michał, Landowski Bogdan, Żółtowski Bogdan Żół   +3 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Who is Facing Higher Increased Demand After the Online-Offline Channel Integration? Evidence from Public Hospitals in China

Risk Management and Healthcare Policy, 2023
Heng Zhao, Xuejing Cao School of Economics and Management, Tongji University, Shanghai, 200092, People’s Republic of ChinaCorrespondence: Xuejing Cao, School of Economics and Management, Tongji University, 1239 Siping Road, Yangpu District, Shanghai ...
Zhao H, Cao X
doaj  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Study on X-ray fluorescence measurement method for Fe content in secondary circuit sampling filter membranes of nuclear power plants

International Journal of Advanced Nuclear Reactor Design and Technology
The measurement of iron (Fe) content in second-loop sampling filter membranes is critical for evaluating corrosion product deposition in pressurized water reactor (PWR) nuclear power plants.
Yu Zhang, Jin-Zhe Zhang, Hong-Yu Chen
doaj   +1 more source

Identify & Prioritize the Barriers of Agility in Enterprizes to Achieve World-Class Production [PDF]

چشم‌انداز مدیریت صنعتی, 2014
One of the major changes in the environment is globalization of economic, industrial and service activities. Globalization has led to expansion of trade between nations. The competitiveness of local markets has been extended to national and international
Hassan Farsijani, Sedigheh Gauomi Ghahroudi   +1 more
doaj  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Distributed Short-Term Traffic Flow Prediction Based on Integrating Federated Learning and TCN

IEEE Access
Existing short-term traffic flow prediction methods are based on centralized learning frameworks, which do not consider the diversity of data, leading to limited predictive performance. Additionally, these methods face challenges related to computational
Tongbin Liu, Yong Wang, Hongyu Zhou, Jian Luo, Fangming Deng   +4 more
doaj   +1 more source