Results 91 to 100 of about 1,163,964 (293)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The Abel summation of the Kontorovich-Lebedev integral representation [PDF]
A new result on the summation of the Kontorovich–Lebedev integral representation in the sense of Abel mean is given.
Petru A. Cojuhari, Alexander M. Gomilko
doaj
Personal technology and the calculus [PDF]
The calculus has long been seen as the pinnacle of mathematical endeavour in secondary schools, and rightly so. For as long as most of can remember, algebra and calculus have formed the trunk of mathematics, without which students can progress no further.
Kissane, B.
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
A Calculus of Mobile Resources
We introduce a calculus of Mobile Resources (MR) tailored for the design and analysis of systems containing mobile, possibly nested, computing devices that may have resource and access constraints, and which are not copyable nor modifiable per se.
Godskesen, J.Chr. +8 more
core +2 more sources
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Higher Mathematics. Operational Calculus [PDF]
Practicum offers additional individual exercises for university students studying Operational Calculus in the course of Higher Mathematics of Igor Sikorsky Kyiv Polytechnic Institute. The study aid contains 30 different variants and each variant consists
Pylypenko, Vita, Massalitina, Уevgeniia
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source

