Results 51 to 60 of about 63,196 (314)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
This study investigates the operational reliability of different types of switching substations within the context of power systems, employing the Monte Carlo method for analysis.
Franjo Pranjić, Peter Virtič
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Considering connectivity in operations journals
PurposeThe purpose of this paper is to examine the coverage of identified topics that represent three key themes of change in management practice. These themes, focused on the new interconnected modern business operation, consist of: cross‐functional or process‐based working, supply networks, and systems thinking.
Niall Piercy, Nigel Caldwell, Nick Rich
openaire +3 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
A Novel Enhanced Connection of AC/AC Powertrain for HEV - Modelling and Simulation Results
The paper deals with a novel enhanced connection of AC/AC powertrain for Hybrid Electric Vehicles (HEV). The substantial contribution of such a connection is the absence of 4QC auxiliary converter needed for autonomous and hybrid operational modes and ...
Branislav Dobrucky +2 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
In connecting to a single Internet Service Provider (ISP), one must consider the possibility of network congestion due to high traffic as well as potential disruptions in the internet connection. Load Balancing Per Connection Classifier (PCC) is a method
Andityo Putra, Anton Anton
doaj +1 more source
Operational connection between predictability and entanglement in entanglement swapping from partially entangled pure states [PDF]
Marcos L. W. Basso, Jonas Maziero
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

