Results 201 to 210 of about 234,200 (268)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Operational Efficiency of Public Hospitals in Greece During the COVID-19 Pandemic: A Comparative Analysis Using DEA and AHP Models. [PDF]

J Mark Access Health Policy
Mitakos A, Mpogiatzidis P.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Spatial correlation network structure of operational efficiency and its driving factors: A case study of star-rated hotels in China. [PDF]

PLoS One
Tao J, Jin X, Cheng H, Wang Q.
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Using Machine Learning and Predictive Artificial Intelligence to Determine Cage Change Frequency for Mice Housed in Individually Ventilated Cages and Drive Vivarium Operational Efficiency. [PDF]

J Am Assoc Lab Anim Sci
Collins JM, Singh B, Zwick ME, Rosati G, Rigamonti M, Urdiales C, Eswaraka JR.   +6 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Streamlining patient flow and enhancing operational efficiency through case management implementation. [PDF]

BMJ Open Qual
Al Harbi S, Aljohani B, Elmasry L, Baldovino FL, Raviz KB, Altowairqi L, Alshlowi S.   +6 more
europepmc   +1 more source

[Impact of surgeon's dominant hand-side consistency with surgical approach on operational efficiency of unilateral biportal endoscopic lumbar discectomy: a prospective cohort study]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Li W, Gao M, Zhang L, Yu Q, Chen X.
europepmc   +1 more source

Evaluating the operational efficiency of NBA teams on franchise value: An assessment of data envelopment analysis. [PDF]

PLoS One
Kim P, Lee SH, Moon J.
europepmc   +1 more source