Results 91 to 100 of about 182,030 (268)

On energy consistent vector hysteresis operators

CoRR
Incremental models for magnetic vector hysteresis have been developed in previous works in accordance with basic principles of thermodynamics. In this paper, we present an equivalent representation of the associated hysteresis operator in terms of a co-energy functional which is useful for magnetic field computations based on a scalar potential.
Herbert Egger, Felix Engertsberger, Lukas Domenig, Klaus Roppert, Manfred Kaltenbacher   +4 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Energy-Arena: A Dynamic Benchmark for Operational Energy Forecasting

6 pages, 5 figures, 1 table.
Kleinebrahm, Max, Berrisch, Jonathan, Eiser, Philipp, Fichtner, Wolf, Hagenmeyer, Veit, Hertel, Matthias, Koster, Nils, Lerch, Sebastian, Mikut, Ralf, Priesmann, Jan, Schienle, Melanie, Schäfer, Benjamin, Weinand, Jann, Ziel, Florian   +13 more
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Building operational energy saving opportunities: A clustering analysis of Ethiopian urban housing

Energy Strategy Reviews
The operational phase of a building consumes a significant amount of energy, making energy efficiency a priority for a sustainable built environment. This study examines operational energy-saving opportunities of Ethiopian urban housing through a cluster
Getahun Ayele Tessema, P.S. Chani, E. Rajasekar   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A Comparison of Pre‐Construction and Operational Wake Loss Estimates for Land‐Based Wind Plants

Wind Energy
The overall bias between pre‐construction energy yield assessment (EYA) estimates of wind plant energy production and the achieved operational production is improving in the wind industry, but uncertainty remains high for individual wind plants.
Eric Simley, M. Jason Fields, Ethan Young, Jeffery Allen, Rob Hammond, Jordan Perr‐Sauer, Nicola Bodini   +6 more
doaj   +1 more source

Operational Digital Shadow for Onshore Wind Energy Systems

Energies
Accurate, uncertainty-aware estimation of instantaneous wind turbine output is a prerequisite for integrating onshore assets into low-emission energy systems, where operational monitoring, energy-performance verification, and cooperative asset management
Nikolaos Sifakis, Antonios Kapenis, Athanasios Kolios, George Arampatzis   +3 more
doaj   +1 more source