Results 71 to 80 of about 182,030 (268)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Energy dependence of the scattering operator II [PDF]

open access: yesCommunications in Mathematical Physics, 1982
We study the energy dependence of the scattering operator for a two-body model of electron scattering from a neutral molecule. We show that the methods of the first paper can be applied even though the dipole moment of the molecule is non-zero, and prove continuity of the scattering operatorS(E) asE varies, in a very strong sense.
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Long-term energy system planning considering short-term operational constraints

open access: yesEnergy Strategy Reviews, 2019
The intermittent nature of renewable energy sources (RESs) brings formidable challenges in the operation of power system. Long-term energy system planning models overlook the impact of renewable intermittency on system operations due to the computational
Ankita Singh Gaur   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Coordinated Optimization and Operational Strategy for Multi-type Energy Storage in Regional Integrated Energy Systems

open access: yesZhongguo dianli
To address the operational optimization issues of multiple heterogeneous energy in regional integrated energy systems, a coordinated operational optimization method for multi-energy storage systems aimed at multi-energy synergistic supply is proposed ...
Mingfei GAO   +4 more
doaj   +1 more source

THE ENERGY COST OF SOME INDUSTRIAL OPERATIONS [PDF]

open access: yesOccupational and Environmental Medicine, 1955
This study forms part of a larger investigation carried out in 1947-48. It aimed at providing a hospi tal department of cardiology with information re garding the physical effort involved in doing various standard operations. This information was for the use of physicians in advising patients and disable ment resettlement officers regarding suitable ...
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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